| | | Saturday, January 17th, 2043 | | Signed free agent RF Telmo Quintero to a minor league contract. |
| Tuesday, November 25th, 2042 | | Drafted 2B Daniel McKeown in the 2042 first-year player draft (Round 1, Pick 11, 11th overall pick). | | Drafted CF Frank Beauchamp in the 2042 first-year player draft (Round 3, Pick 11, 43rd overall pick). | | Drafted 1B Matt Franks in the 2042 first-year player draft (Round 4, Pick 11, 59th overall pick). | | Drafted RF Nolan Ingram in the 2042 first-year player draft (Round 5, Pick 11, 75th overall pick). | | Drafted MR Jimmie Evans in the 2042 first-year player draft (Round 6, Pick 11, 91st overall pick). | | Drafted 2B Arturo Ramos in the 2042 first-year player draft (Round 7, Pick 11, 107th overall pick). | | Drafted MR Toyokazu Ageda in the 2042 first-year player draft (Round 8, Pick 11, 123rd overall pick). | | Drafted C Roberto Trevino in the 2042 first-year player draft (Round 9, Pick 11, 139th overall pick). | | Drafted 1B Ben Hammond in the 2042 first-year player draft (Round 10, Pick 11, 155th overall pick). |
| Monday, November 17th, 2042 | | C Alvaro Dimas received a 1-year contract through automatic renewal worth a total of $300,000. | | SP Mike Whitehead received a 1-year contract through automatic renewal worth a total of $300,000. | | CL Reginald Theunen received a 1-year contract through automatic renewal worth a total of $300,000. | | MR Bartolo Moreno received a 1-year contract through automatic renewal worth a total of $300,000. | | MR James Beamer becomes a free-agent. | | RF John Miller received a 1-year contract through automatic renewal worth a total of $300,000. | | SP John Kreese received a 1-year contract through automatic renewal worth a total of $300,000. | | LF Carlos Sánchez received a 1-year contract through automatic renewal worth a total of $300,000. | | MR George Robledo received a 1-year contract through automatic renewal worth a total of $300,000. | | SP Jose Rodriguez received a 1-year contract through automatic renewal worth a total of $300,000. | | C Angel Soto becomes a free-agent. | | LF Higinio Caminos becomes a free-agent. | | RF Tom Mullenax becomes a free-agent. | | MR Charles Kendall becomes a free-agent. | | 1B Doc Holliday becomes a free-agent. | | SS Dennis Border becomes a free-agent. | | SP Kevin Cannon becomes a free-agent. | | SS Jose Garcia becomes a free-agent. | | LF Gregory McConville becomes a free-agent. |
| Friday, November 14th, 2042 | | SP Tomas Valderrama becomes a free-agent. | | SP Andrea Carolina Garcia+ received a 1-year contract through arbitration worth a total of $4,229,500. | | RF Spencer Belisle becomes a free-agent. | | SP Silvio Rivera received a 1-year contract through arbitration worth a total of $1,705,000. | | 2B Timothy Johnson received a 1-year contract through arbitration worth a total of $450,000. | | RF Omer Kuffrey received a 1-year contract through arbitration worth a total of $450,000. |
| Saturday, October 25th, 2042 | | Signed MR Gary McCormick to a 3-year contract extension worth a total of $7,500,000. | | Signed MR Erin Andrews+ to a 4-year contract extension worth a total of $2,300,000. |
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